What is the role of osteoblasts in the bone healing process?

Osteoblasts play a crucial role in the bone healing process by creating new bone tissue. Their primary function is to synthesize and secrete the bone matrix, which includes proteins such as collagen. During the healing process, osteoblasts are responsible for the formation of trabecular bone, also known as cancellous or spongy bone. This type of bone provides structural support and helps in the ultimately connecting the fragments of bone together, facilitating the overall healing process.

In the stages of healing, after the initial inflammatory phase, osteoblasts become active in the repair phase, where they effectively lay down the new bone matrix, transforming the initial soft callus into a hard bony callus. This is essential for restoring the mechanical integrity of the bone and allowing for a return to normal function. The activity of osteoblasts thus directly contributes to the stabilization and strength of the healing bone.