What is the effect of NSAIDs on soft tissue healing?

The effect of NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) on soft tissue healing is primarily to minimize pain and swelling. NSAIDs work by inhibiting the production of certain enzymes and substances in the body, particularly cyclooxygenase (COX) enzymes, which play a key role in the inflammatory process. By reducing the synthesis of prostaglandins, which are responsible for promoting inflammation, pain, and swelling, NSAIDs relieve discomfort that can often accompany soft tissue injuries.

This property of NSAIDs is crucial in the early stages of healing, as it allows for improved mobility and function of the affected area, potentially facilitating a more effective rehabilitation process. By controlling inflammation and pain, patients may be more inclined to participate in therapeutic exercises, which can further aid recovery.

While the use of NSAIDs is beneficial in managing symptoms, it is important to note that their long-term use must be carefully evaluated, as there could also be implications regarding tissue regeneration that are still being studied. However, in the context of immediate soft tissue healing, the role of NSAIDs in minimizing pain and swelling is well-established.